A plane carrying 81 people, including a Brazilian football team, has crashed on its approach to the city of Medellin in Colombia, officials say.
Details are unclear but some reports say there are survivors.
The chartered plane, flying from Bolivia, was carrying members of the Chapecoense football team, airport officials said.
The team was due to play in the final of the Copa Sudamericana against Medellin team Atletico Nacional.
The first leg of the final of the cup, South America’s second most important club competition, was scheduled for Wednesday, but has now been suspended.
The team, from the city of Chapeco, was promoted to Brazil’s first division in 2014 and reached the final last week after a victory against Argentina’s San Lorenzo.
Reports say the plane, carrying 72 passengers and nine crew, crashed in a mountainous area outside the city shortly before midnight local time (05:00 GMT).
Medellin’s Mayor Federico Gutierrez described it as “a tragedy of huge proportions”, but added it was possible there were survivors.
The Jose Maria Cordova de Rionegro airport, which serves Medellin, posted on its Twitter account: “Confirmed, the aircraft licence number CP2933 was carrying the team @ChapecoenseReal. Apparently there are survivors.”